This book records the landmark performance of The Merchant of Venice in the Venetian Ghetto in 2016, the 400th anniversary of Shakespeare’s death and the 500th anniversary of the Jewish quarter that gave the world the word ‘ghetto’. Practitioners and critics discuss how this multi-ethnic production and its radical choice to cast five actors as Shylock provided the opportunity to respond creatively to Europe’s legacy of antisemitism, racism and difference. They observe how the place and play stand as ambivalent documents of civilization: instruments of intolerance but also sites of cultural exchange.